Are TPBs generally more cost-effective than purchasing the equivalent number of single issues?

Yes, TPBs are generally more cost-effective than purchasing the equivalent number of single issues. While the upfront cost of a TPB is higher than a single issue, the per-issue price within a TPB collection is typically lower. For example, six single issues at $3.99 each would cost nearly $24, whereas a TPB collecting those same six issues might retail for $16.99-$19.99, offering a significant saving.