How does Wolverine's healing factor affect his life story and character development?

Wolverine's healing factor is arguably his defining characteristic. It grants him near-invulnerability, allowing him to survive injuries that would kill ordinary humans. However, it also creates a burden. The constant regeneration can be psychologically taxing, and it has contributed to his long lifespan, which has led to immense accumulated trauma and a sense of isolation. It's a core element of his tragic hero archetype.